Enhancing Cervical Dysplasia Detection with Electrical Impedance Spectroscopy

Electrical Impedance Spectroscopy (EIS) is emerging as a promising adjunct to colposcopy for detecting high-grade cervical intraepithelial neoplasia (CIN). EIS is a diagnostic technique that measures the impedance (resistance to electrical current) of a material across a range of frequencies. This method is particularly useful in medical diagnostics, as it can help distinguish between different types of tissues based on their electrical properties. In the context of cervical cancer screening, EIS is used to improve the accuracy of detecting high-grade CIN.

A comprehensive review of studies from 2005-2023 authored by Panagakis G P, Machairiotis N, Tsiriva M, et al., and published in Cureus, indicates that EIS, combined with colposcopy, offers increased sensitivity and specificity compared to colposcopy alone, improving the detection of precancerous and cancerous lesions. Despite some variability in performance metrics and potential confounders, EIS shows potential for reducing unnecessary invasive procedures and enhancing early detection. Future research, particularly large-scale randomized trials and the integration of artificial intelligence, is needed to further validate and optimize the clinical utility of EIS. Read more here.