HPV Vax Tied to Lower Odds of Cervical Lesion Progression

In a study involving 7,904 women in Denmark undergoing surveillance for cervical intraepithelial neoplasia grade 2 (CIN2), vaccination against human papillomavirus (HPV) before age 20 was associated with a lower risk of progression. The research, conducted between 2007 and 2020, revealed that women vaccinated before age 15 had a 35% lower risk for progression compared to unvaccinated women. Cervical cancer rates were lower in vaccinated women, with all cases in the vaccinated group occurring in those vaccinated after age 20. The findings suggest using HPV vaccination status for risk stratification at the time of CIN2 diagnosis. The study was published in the American Journal of Obstetrics & Gynecology, and discussed by MedScape. Read more here.